Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two Drugs
Completed · Phase 1/Phase 2
Conditions studied: Hepatitis C, Chronic
In brief
The purposes of this Phase 1/2 study are to examine the safety, tolerability, and antiviral activity of ISIS 14803, when given in combination with peginterferon alfa and ribavirin, to patients who either failed to have at least a 100-fold HCV reduction at Week 12 of standard therapy or still have detectable HCV at Week 24.
Key facts
- Study ID
- NCT00062816
- Run by
- Ionis Pharmaceuticals, Inc.
- People needed
- 22
- Starts
- 2003-06-01
- Expected to finish
- 2004-01-01
- Last updated by the study team
- 2022-12-05
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Birmingham Gastroenterology Associates — Birmingham, Alabama, United States
- Mayo Clinic Hospital — Phoenix, Arizona, United States
- Community Clinical Trials — Orange, California, United States
- The Lynn Institute of the Rockies — Colorado Springs, Colorado, United States
- Western States Clinical Research, Inc. — Wheat Ridge, Colorado, United States
- University of Florida — Jacksonville, Florida, United States
- Miami Research Associates, Inc. — Miami, Florida, United States
- Idaho Gastroenterology Assoc. — Boise, Idaho, United States
- IMG Healthcare, LLC — New Orleans, Louisiana, United States
- Beth Israel Deconess Medical Center — Boston, Massachusetts, United States
- FutureCare Studies — Springfield, Massachusetts, United States
- William Beaumont Hospital — Royal Oak, Michigan, United States
- Saint Louis University — St Louis, Missouri, United States
- Cornell Medical Center — New York, New York, United States
- Rochester Institute for Digestive Diseases and Sciences, Inc. — Rochester, New York, United States
- Duke Clinical Research Institute — Durham, North Carolina, United States
- Consultants for Clinical Research — Cincinnati, Ohio, United States
- Blair Gastroenterology Associates — Altoona, Pennsylvania, United States
- Gastroenterology Center of the MidSouth, P.C. — Germantown, Tennessee, United States
- Memphis Gastroenterology Group — Memphis, Tennessee, United States
- Nashville Medical Research Institute — Nashville, Tennessee, United States
- Baylor College of Medicine-VAMC — Houston, Texas, United States
- McGuire VAMC — Richmond, Virginia, United States
- Northwest Gastroenterolgy Assoc. — Bellevue, Washington, United States
- Spokane Digestive Disease Center — Spokane, Washington, United States
Full record on ClinicalTrials.gov
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