The Effect of Weight Loss and Exercise on Knee Osteoarthritis

Completed · Not applicable

Conditions studied: Osteoarthritis, Knee

In brief

This study will evaluate whether a program of weight loss and exercise can help individuals with knee osteoarthritis (OA).

Key facts

Study ID

NCT00061490

Run by

Johns Hopkins University

People needed

160

Starts

2002-09-01

Expected to finish

2006-04-01

Last updated by the study team

2017-09-26

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Knee arthritis
• Pain on > 50 % of days in the month in one or both knees
• Difficulty with activities of daily living due to knee pain
• X-ray documenting knee OA within 1 year prior to study entry
• 15 lbs to 50 lbs overweight

You may not qualify if…

• Significant cardiac, pulmonary, renal, or hepatic disease
• Major psychiatric disease
• ACR functional class IV
• Structured exercise more than once per week for 20 minutes or longer during the 3 months prior to study entry
• Anticipates moving from the area within 18 months of study entry
• Anticipates undergoing knee surgery within 1 year of study entry
• Weight loss of more than 5 kg (11 lbs) in 3 months prior to study entry
• Anorexiant or other medications known to affect metabolism
• Current or planned pregnancy

Where it is running

• Johns Hopkins Bayview Medical Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.