Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer
Completed · Phase 1/Phase 2
Conditions studied: Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
In brief
RATIONALE: Drugs used in chemotherapy such as gemcitabine work in different ways to stop tumor cells from dividing so they stop growing or die. Pemetrexed disodium may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Combining gemcitabine with pemetrexed disodium may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of gemcitabine when given together with pemetrexed disodium to see how well it works in treating patients with unresectable or metastatic biliary tract or gallbladder cancer.
Key facts
- Study ID
- NCT00059865
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 68
- Starts
- 2004-01-01
- Expected to finish
- 2008-02-01
- Last updated by the study team
- 2016-12-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Cancer Center of Kansas, PA - Chanute — Chanute, Kansas, United States
- Cancer Center of Kansas, PA - Dodge City — Dodge City, Kansas, United States
- Cancer Center of Kansas, PA - El Dorado — El Dorado, Kansas, United States
- Cancer Center of Kansas, PA - Kingman — Kingman, Kansas, United States
- Southwest Medical Center — Liberal, Kansas, United States
- Cancer Center of Kansas, PA - Newton — Newton, Kansas, United States
- Cancer Center of Kansas, PA - Parsons — Parsons, Kansas, United States
- Cancer Center of Kansas, PA - Pratt — Pratt, Kansas, United States
- Cancer Center of Kansas, PA - Salina — Salina, Kansas, United States
- Cancer Center of Kansas, PA - Wellington — Wellington, Kansas, United States
- Associates in Womens Health, PA - North Review — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Medical Arts Tower — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Wichita — Wichita, Kansas, United States
- CCOP - Wichita — Wichita, Kansas, United States
- Via Christi Cancer Center at Via Christi Regional Medical Center — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Winfield — Winfield, Kansas, United States
- Green Bay Oncology, Limited - Escanaba — Escanaba, Michigan, United States
- Dickinson County Healthcare System — Iron Mountain, Michigan, United States
- Fairview Ridges Hospital — Burnsville, Minnesota, United States
- Mercy and Unity Cancer Center at Mercy Hospital — Coon Rapids, Minnesota, United States
- Fairview Southdale Hospital — Edina, Minnesota, United States
- Mercy and Unity Cancer Center at Unity Hospital — Fridley, Minnesota, United States
- Minnesota Oncology Hematology, PA - Maplewood — Maplewood, Minnesota, United States
- Virginia Piper Cancer Institute at Abbott - Northwestern Hospital — Minneapolis, Minnesota, United States
- Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center — Robbinsdale, Minnesota, United States
Full record on ClinicalTrials.gov
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