Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell Lymphoma
Completed · Phase 3
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known if combination chemotherapy with vinblastine is more effective than combination chemotherapy with vincristine in treating advanced anaplastic large cell lymphoma. PURPOSE: Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens with either vinblastine or vincristine in treating patients who have newly diagnosed advanced anaplastic large cell lymphoma.
Key facts
- Study ID
- NCT00059839
- Run by
- Children's Oncology Group
- People needed
- 129
- Starts
- 2003-11-01
- Expected to finish
- 2014-07-01
- Last updated by the study team
- 2014-09-22
Who can join
Age: any, up to 20. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Phoenix Children's Hospital — Phoenix, Arizona, United States
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Southern California Permanente Medical Group — Downey, California, United States
- Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California, United States
- Children's Hospital Central California — Madera, California, United States
- Children's Hospital of Orange County — Orange, California, United States
- Sutter Cancer Center — Sacramento, California, United States
- Kaiser Permanente Medical Center - Oakland — Sacramento, California, United States
- Rady Children's Hospital - San Diego — San Diego, California, United States
- UCSF Helen Diller Family Comprehensive Cancer Center — San Francisco, California, United States
- Stanford Cancer Center — Stanford, California, United States
- Children's Hospital Center for Cancer and Blood Disorders — Aurora, Colorado, United States
- Presbyterian - St. Luke's Medical Center — Denver, Colorado, United States
- Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center — Farmington, Connecticut, United States
- Alfred I. duPont Hospital for Children — Wilmington, Delaware, United States
- Children's National Medical Center — Washington D.C., District of Columbia, United States
- Broward General Medical Center Cancer Center — Fort Lauderdale, Florida, United States
- Lee Cancer Care of Lee Memorial Health System — Fort Myers, Florida, United States
- Memorial Cancer Institute at Memorial Regional Hospital — Hollywood, Florida, United States
- Nemours Children's Clinic — Jacksonville, Florida, United States
- University of Miami Sylvester Comprehensive Cancer Center - Miami — Miami, Florida, United States
- Miami Children's Hospital — Miami, Florida, United States
- Baptist-South Miami Regional Cancer Program — Miami, Florida, United States
- Florida Hospital Cancer Institute at Florida Hospital Orlando — Orlando, Florida, United States
- Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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