Treatment of Cholestatic Pruritus With Sertraline

Completed · Phase 2

Conditions studied: Pruritus, Liver Cirrhosis, Biliary, Hepatitis C

In brief

The goal of this study is to find an effective and well-tolerated medical therapy for itching due to liver disease. Persons with primary biliary cirrhosis or chronic hepatitis C are currently being enrolled in the study. Persons participating in the study are given sertraline, a medication which is also often used for depression,to treat their itching. The dose is gradually increased as the effect on itching and any other potential side effects are carefully monitored.

Key facts

Study ID
NCT00058903
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
People needed
40
Starts
2003-04-01
Expected to finish
2005-03-01
Last updated by the study team
2010-01-13

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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