Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer
Completed · Phase 2
Conditions studied: Head and Neck Cancer, Oral Complications of Radiation Therapy, Radiation Toxicity
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy in different ways may cause less damage to normal tissue, prevent or lessen mouth dryness, and may help patients live more comfortably. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of specialized radiation therapy techniques with or without chemotherapy in reducing mouth dryness in patients who have nasopharyngeal cancer.
Key facts
- Study ID
- NCT00057785
- Run by
- Radiation Therapy Oncology Group
- People needed
- 68
- Starts
- 2003-02-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2017-02-17
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Comprehensive Cancer Center at University of Alabama at Birmingham — Birmingham, Alabama, United States
- University of California Davis Cancer Center — Davis, California, United States
- Radiological Associates of Sacramento Medical Group, Incorporated — Sacramento, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Northeast Georgia Medical Center — Gainesville, Georgia, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- Siteman Cancer Center at Barnes-Jewish Hospital — St Louis, Missouri, United States
- Monmouth Medical Center — Long Branch, New Jersey, United States
- Albuquerque Regional Medical Center at Lovelace Sandia Health System — Albuquerque, New Mexico, United States
- Akron City Hospital — Akron, Ohio, United States
- Kimmel Cancer Center at Thomas Jefferson University - Philadelphia — Philadelphia, Pennsylvania, United States
- Fox Chase-Temple Cancer Center — Philadelphia, Pennsylvania, United States
- CCOP - MainLine Health — Wynnewood, Pennsylvania, United States
- M.D. Anderson Cancer Center at University of Texas — Houston, Texas, United States
- Wilford Hall Medical Center — Lackland Air Force Base, Texas, United States
- McKay-Dee Hospital Center — Ogden, Utah, United States
- Medical College of Wisconsin Cancer Center — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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