Comparing Effects of 3 Sources of Garlic on Cholesterol Levels

Completed · Phase 2/Phase 3

Conditions studied: Hypercholesterolemia

In brief

The purpose of this study is to determine whether fresh garlic can positively affect cholesterol in adults with moderately high cholesterol levels. This study will also determine whether the same effects can be found for two main types of garlic supplements: a dried powdered garlic (designed to yield the same effect as fresh garlic) and an aged garlic extract preparation.

Key facts

Study ID

NCT00056511

Run by

National Center for Complementary and Integrative Health (NCCIH)

People needed

220

Starts

2002-05-01

Expected to finish

2005-04-01

Last updated by the study team

2006-08-18

Who can join

Age: 30 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• LDL-C 130-190 mg/dL (fasting single sample)
• BMI (body mass index) 19-30 kg/m2 (42-66 lb/m2)
• Weight stable for last 2 months
• Not actively on a weight loss plan
• Ethnicity representative of local population
• No plans to move from the area over the next 9 months

You may not qualify if…

• Pregnant, lactating, within 6 months postpartum, or planning to become pregnant in the next year
• Diabetes (type I or II) or history of gestational diabetes
• Heart disease
• Active neoplasms
• Renal or liver disease
• Hyperthyroidism or hypothyroidism
• Lipid lowering medications (known to affect lipid metabolism, platelet function, or antioxidant status)
• Blood pressure medications
• Excessive alcohol intake (self reported, more than 3 drinks/day)
• Currently under psychiatric care or severely clinically depressed

Where it is running

• Stanford Center for Research in Disease Prevention — Palo Alto, California, United States

Full record on ClinicalTrials.gov

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