An Open Label Study of a Peptide Vaccine in Patients With Stage III Colon Cancer

Completed · Phase 1

Conditions studied: Colonic Neoplasms, Colorectal Neoplasms

In brief

EP2101 is a new cancer vaccine containing 10 different peptide antigens. The vaccine is designed to activate the immune system to develop a response against tumor cells in order to delay or prevent the recurrence of cancer. This study will test the safety and measure the level of immune stimulating capability of EP2101 in patients with Colon Cancer.

Key facts

Study ID

NCT00054912

Run by

Epimmune

People needed

18

Starts

2003-02-01

Last updated by the study team

2008-04-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed diagnosis of Colon Cancer, stage III
• At least four weeks following prior standard treatment, with no evidence of disease
• Must use adequate birth control

You may not qualify if…

• Prior cancer vaccine therapy or concurrent participation in any other investigational study
• A history of HIV, Hepatitis B or C, or any other acute medical condition which may compromise patient safety or the activity of the study vaccine treatment
• A history of adverse reactions following administration of any vaccines, or a history of hypersensitivity to any components of the study vaccine
• Women who are pregnant, intend to become pregnant, or who are breast feeding

Where it is running

• University of Southern California School of Medicine — Los Angeles, California, United States
• University of California, San Diego — San Diego, California, United States
• Cancer Centers of Florida — Orlando, Florida, United States
• New York Oncology Hematology — Albany, New York, United States
• Duke University Medical Center — Durham, North Carolina, United States
• Mary Crowley Medical Research Center — Dallas, Texas, United States
• Tyler Cancer Center — Tyler, Texas, United States
• University of Washington — Seattle, Washington, United States
• Cancer Care Northwest — Spokane, Washington, United States

Full record on ClinicalTrials.gov

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