Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery

Completed · Not applicable

Conditions studied: Cardiovascular Disease, Coronary Artery Disease

In brief

VA patients with coronary artery disease and who have agreed to undergo coronary artery bypass graft surgery would be randomized to receive either radial artery or saphenous vein to the study vessel. The primary outcome variable is graft patency at one year.

Key facts

Study ID

NCT00054847

Run by

US Department of Veterans Affairs

People needed

733

Starts

2003-02-01

Expected to finish

2010-02-01

Last updated by the study team

2014-05-05

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients needing coronary artery bypass grafts.

You may not qualify if…

• Patients who require only a single vessel bypass and in whom the internal mammary artery will be used for that graft
• Patients with previous stripping and ligation of saphenous veins and in whom no venous conduit is available for bypass
• Patients with Raynaud's symptoms
• Patients who have a creatinine above 2.0 mg/dL or require hemodialysis
• Patients with a positive Allen test
• Patients with cardiogenic shock
• Patients who are unable to give consent
• Patients allergic to contrast material
• Patients undergoing repeat CABG or any form of robotic surgery
• Patients who do not have full use of both arms
• Patients who are pregnant
• Patients with neurologic or musculoskeletal disease affecting the arm
• Patients who refuse to participate
• Patient requires any concomitant valve operation in the mitral, aortic, or pulmonary position. Isolated tricuspid annuloplasty is acceptable, but tricuspid valve replacement excludes the patient from consideration.
• Patient requires concomitant Dor or Maze procedure
• Patient is in another research study
• No suitable radial target (there is no non-LAD vessel with a >70% stenosis)

Where it is running

• VA Medical Center, Birmingham — Birmingham, Alabama, United States
• Southern Arizona VA Health Care System — Tucson, Arizona, United States
• Central Arkansas VHS Eugene J. Towbin Healthcare Ctr, Little Rock — No. Little Rock, Arkansas, United States
• Edward Hines, Jr. VA Hospital — Hines, Illinois, United States
• Southeast Veterans Healthcare System, New Orleans — New Orleans, Louisiana, United States
• VA Boston Healthcare System, Brockton Campus — Brockton, Massachusetts, United States
• VA Ann Arbor Healthcare System — Ann Arbor, Michigan, United States
• VA Medical Center, Minneapolis — Minneapolis, Minnesota, United States
• New Mexico VA Health Care System, Albuquerque — Albuquerque, New Mexico, United States
• Michael E. DeBakey VA Medical Center (152) — Houston, Texas, United States
• Hunter Holmes McGuire VA Medical Center — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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