Prostaglandin E1 (Liprostin) Treatment With Lower Limb Angioplasty for Peripheral Arterial Occlusive Disease

Status unconfirmed · Phase 2

Conditions studied: Peripheral Vascular Disease

In brief

This is the first clinical research trial in which intravenous Prostaglandin E1 (PGE1 is a vasoactive hormone) will be used as supportive treatment along with the angioplasty procedure to treat or open up a blocked artery within one lower limb or the most affected of two limbs in subjects with Peripheral Arterial Occlusive Disease.

Key facts

Study ID

NCT00053716

Run by

Endovasc

People needed

12

Starts

2003-02-01

Expected to finish

2003-08-01

Last updated by the study team

2007-03-07

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female subjects, 18 years and older
• Diagnosis of Peripheral Arterial Occlusive Disease [PAOD]
• Subject is a candidate for immediate angioplasty of the lower limb
• Subject must complete 2 treadmill tests at Screen in which walking distance is limited by PAOD and not due to angina or fatigue

You may not qualify if…

• Lower limb peripheral re-vascularization procedures in past 3 months
• History of myocardial infarction in the past 6 months
• Malignant disease, uncontrolled hypertension or Class III heart failure
• Aortic occlusion, thrombosed popliteal aneurysm, severe hemorrhagic disorder, or a long iliac occlusion

Where it is running

• Memorial Hermann Hospital — Houston, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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