Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium
Completed · Phase 2
Conditions studied: Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
In brief
RATIONALE: Pemetrexed disodium may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Drugs used in chemotherapy, such as gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining pemetrexed disodium with gemcitabine may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining pemetrexed disodium with gemcitabine in treating patients who have advanced cancer of the urothelium.
Key facts
- Study ID
- NCT00053209
- Run by
- Eastern Cooperative Oncology Group
- People needed
- 46
- Starts
- 2004-08-10
- Expected to finish
- 2009-05-01
- Last updated by the study team
- 2023-06-22
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Boulder Community Hospital — Boulder, Colorado, United States
- Penrose Cancer Center at Penrose Hospital — Colorado Springs, Colorado, United States
- Porter Adventist Hospital — Denver, Colorado, United States
- Presbyterian - St. Luke's Medical Center — Denver, Colorado, United States
- St. Joseph Hospital — Denver, Colorado, United States
- Rose Medical Center — Denver, Colorado, United States
- CCOP - Colorado Cancer Research Program, Incorporated — Denver, Colorado, United States
- Swedish Medical Center — Englewood, Colorado, United States
- Sky Ridge Medical Center — Lone Tree, Colorado, United States
- Hope Cancer Care Center at Longmont United Hospital — Longmont, Colorado, United States
- St. Mary-Corwin Regional Medical Center — Pueblo, Colorado, United States
- North Suburban Medical Center — Thornton, Colorado, United States
- Yale Comprehensive Cancer Center at Yale University School of Medicine — New Haven, Connecticut, United States
- Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- St. Francis Hospital — Wilmington, Delaware, United States
- Baptist Cancer Institute - Jacksonville — Jacksonville, Florida, United States
- Watson Clinic, LLC — Lakeland, Florida, United States
- Hematology and Oncology of Northeast Georgia — Athens, Georgia, United States
- MBCCOP-Medical College of Georgia Cancer Center — Augusta, Georgia, United States
- Rush-Copley Cancer Care Center — Aurora, Illinois, United States
- Hinsdale Hematology Oncology Associates — Hinsdale, Illinois, United States
- Joliet Oncology Hematology Associates, Limited - West — Joliet, Illinois, United States
- Regional Cancer Center at Memorial Medical Center — Springfield, Illinois, United States
- Aurora Presbyterian Hospital — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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