Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer

Completed · Phase 3

Conditions studied: Esophageal Cancer, Gastric Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy after surgery may kill any remaining tumor cells following surgery. It is not yet known which chemotherapy and radiation therapy regimen is more effective in treating stomach or esophageal cancer. PURPOSE: Randomized phase III trial to compare two different chemotherapy and radiation therapy regimens in treating patients who have undergone surgery for stomach or esophageal cancer.

Key facts

Study ID

NCT00052910

Run by

Alliance for Clinical Trials in Oncology

People needed

546

Starts

2002-12-01

Expected to finish

2016-12-01

Last updated by the study team

2020-05-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Providence Cancer Center at Providence Hospital — Mobile, Alabama, United States
• Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
• Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona, United States
• Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas, United States
• Ben E. Owens Cancer Treatment Center at St. Bernard's Medical Center — Jonesboro, Arkansas, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Kaiser Permanente - Deer Valley — Antioch, California, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• East Bay Radiation Oncology Center — Castro Valley, California, United States
• Eden Medical Center — Castro Valley, California, United States
• Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Kaiser Permanente - Fremont — Fremont, California, United States
• Valley Medical Oncology — Fremont, California, United States
• Glendale Memorial Hospital Comprehensive Cancer Center — Glendale, California, United States
• Kaiser Permanente Medical Center - Hayward — Hayward, California, United States
• Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
• Contra Costa Regional Medical Center — Martinez, California, United States
• Memorial Medical Center — Modesto, California, United States
• Community Hospital of the Monterey Peninsula Comprehensive Cancer Center — Monterey, California, United States
• Camino Medical Group - Treatment Center — Mountain View, California, United States
• El Camino Hospital Cancer Center — Mountain View, California, United States
• Highland General Hospital — Oakland, California, United States
• Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
• Regional Medical Center — Anniston, Alabama, United States

Full record on ClinicalTrials.gov

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