Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Completed · Phase 2
Conditions studied: Prostate Cancer
In brief
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Estramustine may fight prostate cancer by reducing the production of androgens. Exisulind may stop the growth of prostate cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining these therapies may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining estramustine with exisulind and docetaxel in treating patients who have metastatic prostate cancer that has not responded to hormone therapy.
Key facts
- Study ID
- NCT00052845
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 80
- Starts
- 2002-11-01
- Expected to finish
- 2009-04-01
- Last updated by the study team
- 2016-07-01
Who can join
Age: 18 and older. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
- Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center — Los Angeles, California, United States
- Veterans Affairs Medical Center - San Diego — San Diego, California, United States
- UCSF Comprehensive Cancer Center — San Francisco, California, United States
- Veterans Affairs Medical Center - San Francisco — San Francisco, California, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- Lombardi Cancer Center of Georgetown University Medical Center — Washington D.C., District of Columbia, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- Veterans Affairs Medical Center - Washington, DC — Washington D.C., District of Columbia, United States
- Broward General Medical Center — Fort Lauderdale, Florida, United States
- Memorial Regional Hospital Comprehensive Cancer Center — Hollywood, Florida, United States
- CCOP - Mount Sinai Medical Center — Miami Beach, Florida, United States
- Florida Hospital Cancer Institute — Orlando, Florida, United States
- Palm Beach Cancer Institute — West Palm Beach, Florida, United States
- MBCCOP - University of Illinois at Chicago — Chicago, Illinois, United States
- Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Louis A. Weiss Memorial Hospital — Chicago, Illinois, United States
- West Suburban Center for Cancer Care — River Forest, Illinois, United States
- Saint Anthony Medical Center — Rockford, Illinois, United States
- Fort Wayne Medical Oncology and Hematology, Incorporated — Fort Wayne, Indiana, United States
- CCOP - Northern Indiana CR Consortium — South Bend, Indiana, United States
- Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
- Baptist Hospital East - Louisville — Louisville, Kentucky, United States
- Northeast Alabama Regional Medical Center — Anniston, Alabama, United States
Full record on ClinicalTrials.gov
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