Aerobic Exercise Intervention for Knee Osteoarthritis

Completed · Not applicable

Conditions studied: Osteoarthritis

In brief

This trial will test if walking or bicycling exercise is effective as a non-surgical treatment option for patients with knee osteoarthritis.

Key facts

Study ID

NCT00049816

Run by

Mayo Clinic

People needed

306

Starts

2002-10-01

Expected to finish

2007-04-01

Last updated by the study team

2013-05-17

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current symptoms of chronic (6 months), stable pain and/or stiffness in one or both knees during weight-bearing activities
• Involved joint is primary factor limiting physical or functional activity
• Radiographic signs of mild or moderate arthritis
• Mild joint space narrowing (at least 2mm remaining)

You may not qualify if…

• Current participation in a regular exercise program
• Existing medical condition that would preclude increased physical activity
• Subjective complaint of instability (giving way)
• Ligamentous instability greater than Grade I
• Knee flexion contracture greater than 15 degrees
• Asymptomatic osteoarthritis of both knees, incapacitating arthritis, or inflammatory arthritis
• Major reconstructive surgery on a lower extremity joint
• Multiple major joint involvement
• Any condition which severely limits local ambulation, such as amputation or stroke
• Gait aids used majority of time for ambulation
• Cannot use step-over-step techniques in either ascending or descending stair conditions
• Not able to undergo MRI scan (e.g., cardiac pacemaker)
• Dementia or inability to give informed consent as determined by a Folstein Mini Mental score greater than 24

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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