Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Completed · Phase 2

Conditions studied: Pancreatic Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy with radiation therapy before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Randomized phase II trial to compare the effectiveness of two different regimens combining chemotherapy with radiation therapy in treating patients who are undergoing surgery for locally advanced pancreatic cancer.

Key facts

Study ID

NCT00049348

Run by

Eastern Cooperative Oncology Group

Starts

2003-10-13

Expected to finish

2009-05-01

Last updated by the study team

2023-06-15

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Yale Comprehensive Cancer Center — New Haven, Connecticut, United States
• Lynn Regional Cancer Center of Boca Raton Community Hospital — Boca Raton, Florida, United States
• University of Florida Shands Cancer Center — Gainesville, Florida, United States
• Mayo Clinic - Jacksonville — Jacksonville, Florida, United States
• Emory University Hospital - Atlanta — Atlanta, Georgia, United States
• Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
• Medical Center of Central Georgia — Macon, Georgia, United States
• Rush-Copley Cancer Care Center — Aurora, Illinois, United States
• St. Joseph Medical Center — Bloomington, Illinois, United States
• Graham Hospital — Canton, Illinois, United States
• Memorial Hospital — Carthage, Illinois, United States
• Hematology and Oncology Associates — Chicago, Illinois, United States
• Robert H. Lurie Comprehensive Cancer Center at Northwestern University — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Lakeside Chicago — Chicago, Illinois, United States
• Mercy Hospital and Medical Center — Chicago, Illinois, United States
• Swedish Covenant Hospital — Chicago, Illinois, United States
• St. Anthony's Memorial Hospital — Effingham, Illinois, United States
• Eureka Hospital — Eureka, Illinois, United States
• Evanston Northwestern Health Care - Evanston Hospital — Evanston, Illinois, United States
• Galesburg Clinic — Galesburg, Illinois, United States
• Galesburg Cottage Hospital — Galesburg, Illinois, United States
• InterCommunity Cancer Center of Western Illinois — Galesburg, Illinois, United States
• Mason District Hospital — Havana, Illinois, United States
• Hopedale Medical Complex — Hopedale, Illinois, United States
• CCOP - Mayo Clinic Scottsdale Oncology Program — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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