Safety and Efficacy of IDEC-114 in Combination With Rituxan in the Treatment of Non-Hodgkin's Lymphoma
Completed · Phase 1/Phase 2
Conditions studied: Non-Hodgkin's Lymphoma
In brief
To determine what side effects and what clinical effect, if any, the administration of this investigational product, IDEC-114 in combination with Rituxan® \[Rituxan® as a single agent is approved by the United States Food and Drug Administration (FDA) to treat patients with relapsed or refractory follicular NHL\], has in this patient population.
Key facts
- Study ID
- NCT00048555
- Run by
- Biogen
- People needed
- 90
- Starts
- 2002-11-01
- Expected to finish
- 2010-11-01
- Last updated by the study team
- 2013-09-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Signed IRB-approved informed consent
- Greater than or equal to 18 years of age
- Proof of follicular lymphoma
- Progressive disease requiring treatment after at least 1 prior standard therapy
- Acceptable hematologic status, liver function, and renal function
- Patients of reproductive potential must agree to follow accepted birth control methods during treatment and for 3 months after completion of treatment
You may not qualify if…
- No response to prior Rituxan® or Rituxan®-containing regimen
- Presence of CLL or CNS lymphoma
- Known history of HIV infection or AIDS
- Prior diagnosis of aggressive NHL or mantle-cell lymphoma
- Serious nonmalignant disease
- Pregnant or currently breast feeding
Where it is running
- Research site — Birmingham, Alabama, United States
- Research site — Tucson, Arizona, United States
- Research site — Los Angeles, California, United States
- Research site — Newport Beach, California, United States
- Research site — San Diego, California, United States
- Research site — Aurora, Colorado, United States
- Research site — Washington D.C., District of Columbia, United States
- Research site — Tampa Bay, Florida, United States
- Research site — Chicago, Illinois, United States
- Research site — Maywood, Illinois, United States
- Research site — Boston, Massachusetts, United States
- Research site — Detroit, Michigan, United States
- Research site — Rochester, Minnesota, United States
- Research site — Omaha, Nebraska, United States
- Research site — Buffalo, New York, United States
- Research site — New York, New York, United States
- Research site — Rochester, New York, United States
- Research site — Durham, North Carolina, United States
- Research site — Philadelphia, Pennsylvania, United States
- Research site — Columbia, South Carolina, United States
- Research site — Houston, Texas, United States
- Research site — Charlottesville, Virginia, United States
Full record on ClinicalTrials.gov
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