Celecoxib and Radiation Therapy in Treating Patients With Locally Advanced Non-Small Cell Lung Cancer

Completed · Phase 1/Phase 2

Conditions studied: Lung Cancer

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Celecoxib may stop the growth of tumor cells by stopping blood flow to the tumor and may make the tumor cells more sensitive to radiation therapy. PURPOSE: Phase I/II trial to study the effectiveness of combining celecoxib with radiation therapy in treating patients who have locally advanced non-small cell lung cancer.

Key facts

Study ID

NCT00046839

Run by

Radiation Therapy Oncology Group

People needed

21

Starts

2002-07-01

Last updated by the study team

2015-11-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Memorial Hospital Cancer Center — Colorado Springs, Colorado, United States
• University of Florida Shands Cancer Center — Gainesville, Florida, United States
• Baptist Cancer Institute - Jacksonville — Jacksonville, Florida, United States
• University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
• Regional Radiation Oncology Center at Rome — Rome, Georgia, United States
• Ingalls Cancer Care Center at Ingalls Memorial Hospital — Harvey, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Wendt Regional Cancer Center at Finley Hospital — Dubuque, Iowa, United States
• Markey Cancer Center at University of Kentucky Chandler Medical Center — Lexington, Kentucky, United States
• West Michigan Cancer Center — Kalamazoo, Michigan, United States
• Virginia Piper Cancer Institute at Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• Park Nicollet Clinic — Saint Louis Park, Minnesota, United States
• CCOP - Kansas City — Kansas City, Missouri, United States
• St. John's Regional Health Center — Springfield, Missouri, United States
• Monmouth Medical Center — Long Branch, New Jersey, United States
• Fox Chase Virtua Health Cancer Program - Marlton — Mount Holly, New Jersey, United States
• Albuquerque Regional Medical Center at Lovelace Sandia Health System — Albuquerque, New Mexico, United States
• University of New Mexico Cancer Research and Treatment Center — Albuquerque, New Mexico, United States
• Trinity Cancer Care Center — Minot, North Dakota, United States
• Akron City Hospital at Summa Health System — Akron, Ohio, United States
• Radiation Oncology Center — Alliance, Ohio, United States
• Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford — Salem, Ohio, United States
• Cancer Treatment Center — Wooster, Ohio, United States
• Natalie Warren Bryant Cancer Center at St. Francis Hospital — Tulsa, Oklahoma, United States

Full record on ClinicalTrials.gov

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