Efficacy and Safety Study of OSI-211 (Liposomal Lurtotecan) to Treat Recurrent Small Cell Lung Cancer

Completed · Phase 2

Conditions studied: SCLC, Carcinoma, Small Cell

In brief

The purpose of this study is to determine whether OSI-211 (Liposomal Lurtotecan) is an effective and safe treatment for patients with recurrent small cell lung cancer.

Key facts

Study ID

NCT00046787

Run by

Astellas Pharma Inc

People needed

47

Starts

2002-09-01

Expected to finish

2003-02-01

Last updated by the study team

2011-10-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Confirmed recurrent small cell lung cancer.
• One prior treatment of chemotherapy.
• At least three weeks since last chemotherapy treatment and recovery from any related side effects.
• At least three weeks since last chest radiotherapy and at least 10 days since head irradiation and recovery from acute side effects.
• At least one target tumor less than or equal to 20 mm (or less than or equal to 10 mm on spiral CT-scan).
• If a patient has had previous documented Central Nervous System (CNS) involvement, only controlled disease is acceptable.

You may not qualify if…

• Superior vena cava syndrome.

Where it is running

• Arizona Clinical Research Center, Inc. — Tucson, Arizona, United States
• University of Colorado Health Sciences Center — Denver, Colorado, United States
• Baptist Hospital Regional Cancer Ctr. — Knoxville, Tennessee, United States
• Vanderbilt Clinical Trials Office — Nashville, Tennessee, United States
• Nottingham City Hospital — Nottingham, Nottinghamshire, United Kingdom
• Clatterbridge Centre for Oncology — Bebington, Wirral, United Kingdom
• Aberdeen Royal Infirmary — Aberdeen, United Kingdom
• Guys Hospital — London, United Kingdom
• Christie Hospital — Manchester, United Kingdom
• Northern Centre for Cancer Research, Newcastle General Hospital — Newcastle upon Tyne, United Kingdom

Full record on ClinicalTrials.gov

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