ABI-007 in Taxol Resistant Patients With Metastatic Breast Cancer

Completed · Phase 2

Conditions studied: Breast Neoplasms, Metastases, Neoplasm

In brief

The anticancer agent paclitaxel (marketed as Taxol) has shown remarkable activity against metastatic breast cancer. However, the Taxol formulation requires prolonged administration times, and there are safety problems that have been attributed to the solvent rather than the active ingredient, paclitaxel. This is a new formulation of paclitaxel that has been found to have fewer safety problems than Taxol, and may be administered safely at higher doses. This study will investigate the safety and efficacy of this new formulation of paclitaxel given intravenously once a week for three weeks, followed by a rest week. This cycle will be repeated until safety problems or treatment failure require that the patient stop therapy.

Key facts

Study ID
NCT00046514
Run by
Celgene Corporation
People needed
100
Starts
2001-06-01
Last updated by the study team
2016-12-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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