A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse)

Completed · Phase 3 · Has a placebo group

Conditions studied: Myocardial Infarction

In brief

The purpose of this study is to determine whether abciximab given in combination with reteplase, before patients have a coronary intervention (a standard treatment where a catheter is inserted into the heart artery to get blood flowing past the clot), is safe and effective in the treatment of heart attacks compared to only abciximab given during coronary intervention.

Key facts

Study ID

NCT00046228

Run by

Centocor, Inc.

People needed

2461

Starts

2002-08-01

Expected to finish

2008-01-01

Last updated by the study team

2014-07-31

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have prolonged, continuous (lasting at least 20 minutes) signs and symptoms of A heart attack not eliminated with nitrates and onset within 6 hours of randomization,and confirmation by Electrocardiogram

You may not qualify if…

• Low risk clinical presentation
• patients who will not be undergoing a catherization within 4 hours of the qualifying Electrocardiogram

Where it is running

• Study site — Covina, California, United States
• Study site — Modesto, California, United States
• Study site — Newark, Delaware, United States
• Study site — Washington D.C., District of Columbia, United States
• Study site — Clearwater, Florida, United States
• Study site — Jacksonville, Florida, United States
• Study site — Miami, Florida, United States
• Study site — St. Petersburg, Florida, United States
• Study site — Tallahassee, Florida, United States
• Study site — Weston, Florida, United States
• Study site — Harvey, Illinois, United States
• Study site — Rock Island, Illinois, United States
• Study site — Lexington, Kentucky, United States
• Study site — Louisville, Kentucky, United States
• Study site — New Orleans, Louisiana, United States
• Study site — Lewiston, Maine, United States
• Study site — Worcester, Massachusetts, United States
• Study site — Ann Arbor, Michigan, United States
• Study site — Pontiac, Michigan, United States
• Study site — St Louis, Missouri, United States
• Study site — Brooklyn, New York, United States
• Study site — Flushing, New York, United States
• Study site — Mineola, New York, United States
• Study site — New York, New York, United States
• Study site — Phoenix, Arizona, United States

Full record on ClinicalTrials.gov

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