Evaluation of the Effect on Glucose Control and the Safety and Tolerability of AC2993 in Patients With Type 2 Diabetes Mellitus

Completed · Phase 2 · Has a placebo group

Conditions studied: Diabetes Mellitus, Non-Insulin-Dependent

In brief

This is a multicenter, randomized, blinded, placebo-controlled, short-term, dose-response study to examine the effects on glucose control of AC2993 as compared to placebo in patients with type 2 diabetes. Patients will be individuals with type 2 diabetes treated with metformin for at least 3 months prior to screening. Patients whose diabetes management consists of diet and exercise will also be eligible for this study.

Key facts

Study ID

NCT00044694

Run by

AstraZeneca

People needed

156

Starts

2002-08-01

Expected to finish

2003-05-01

Last updated by the study team

2015-02-20

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with type 2 diabetes
• Treated with diet and exercise alone or with metformin for at least 3 months prior to screening
• BMI 27-45 kg/m\^2
• HbA1c between 7.0 % and 8.0 %

You may not qualify if…

• Treated with other oral anti-diabetic agents other than metformin within 3 months of screening
• Patients previously treated with AC2993
• Patients presently treated with insulin

Where it is running

• Innovative Clinical Trials — Birmingham, Alabama, United States
• Healthsouth Clinical Research — Birmingham, Alabama, United States
• Endocrinology Clinic of O.C. — Anaheim, California, United States
• Pioneer Medical Group — Bellflower, California, United States
• International Clinical Research Network — Chula Vista, California, United States
• Bautista Research and Medical Clinic — Fresno, California, United States
• Whittier Institute for Diabetes — La Jolla, California, United States
• Richard Cherlin, M.D. — Los Gatos, California, United States
• Dr. Martinez Medical Clinic — Moreno Valley, California, United States
• Anshutz Outpatient Pavilion — Aurora, Colorado, United States
• Diagnostic Clinic — Clearwater, Florida, United States
• Radiant Research-Gainsville — Gainsville, Florida, United States
• Jacksonville Center for Clinical Research — Jacksonville, Florida, United States
• Radiant Research-Pinellas Park — Pinellas Park, Florida, United States
• Clinical Research Group of North Georgia — Blairsville, Georgia, United States
• East-West Medical Research Institute — Honolulu, Hawaii, United States
• Radiant Research-Honolulu — Honolulu, Hawaii, United States
• Radiant Research-Boise — Boise, Idaho, United States
• Cedar-Crosse Research Center — Chicago, Illinois, United States
• Northshore Medical Research, LLC — Covington, Louisiana, United States
• Medical Research Institute — Slidell, Louisiana, United States
• Melvin Kramer, MD — Concord, Massachusetts, United States
• Radiant Research-Edina — Edina, Minnesota, United States
• Mississippi Medical Research, LLC — Gulfport, Mississippi, United States
• The Center for Pharmaceutical Research — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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