Treatments for Depression: Drug Versus Psychotherapy

Completed · Phase 3 · Has a placebo group

Conditions studied: Depression

In brief

This 4-8 month study, with a 2-year follow up period, will compare sertraline (Zoloft®), venlafaxine (Effexor®), supportive-expressive psychotherapy, and placebo to determine which is more effective in treating major depression.

Key facts

Study ID

NCT00043550

Run by

University of Pennsylvania

People needed

156

Starts

2001-11-01

Expected to finish

2009-06-01

Last updated by the study team

2017-06-02

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Major Depressive Disorder diagnosis

You may not qualify if…

• Psychotic or bipolar disorder diagnosis
• Substance dependence in the last 6 months

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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