Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

Completed

Conditions studied: HIV Infections

In brief

IMPAACT P1026s is a Phase IV prospective clinical study to evaluate the pharmacokinetics (PKs) of antiretroviral (ARV) and tuberculosis (TB) medications in pregnant women and their infants. (Pharmacokinetics are the various interactions between a drug and the body.) This study also evaluated the PKs of certain ARVs in postpartum women before and after starting hormonal contraceptives. The PKs of these drugs were evaluated by measuring the amount of medicine present in blood and/or vaginal secretions.

Key facts

Study ID
NCT00042289
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
People needed
1578
Starts
2003-06-09
Expected to finish
2020-09-30
Last updated by the study team
2025-12-02

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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