Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures

Completed · Phase 2/Phase 3

Conditions studied: Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia, Graft Occlusion, Vascular, Hyperplasia

In brief

The purpose of this study is to determine the efficacy of graft pretreatment with the E2F decoy, CGT003, as compared to placebo, on the occurrence of graft failure among patients who receive autogenous vein grafts to treat chronic critical limb ischemia; on the occurrence of clinically significant graft stenosis (more than or equal to 70%); and on the incidence of critical limb ischemia (e.g., gangrene, non-healing ischemic ulcers or ischemic rest pain).

Key facts

Study ID
NCT00041925
Run by
Anesiva, Inc.
People needed
1400
Starts
2001-11-01
Expected to finish
2004-11-01
Last updated by the study team
2005-07-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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