Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma
Completed · Phase 2
Conditions studied: Lymphoma
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Antiviral therapy may kill viruses such as HTLV-1 that can cause cancer. Interferon alfa may interfere with the growth of cancer cells. Combining chemotherapy with antiviral drugs and interferon alfa may be effective in treating adult T-cell leukemia/lymphoma. PURPOSE: Phase II trial to determine the effectiveness of combination chemotherapy followed by antiviral therapy and interferon alfa in treating patients who have adult T-cell leukemia/lymphoma caused by HTLV-1.
Key facts
- Study ID
- NCT00041327
- Run by
- AIDS Malignancy Consortium
- People needed
- 19
- Starts
- 2002-10-01
- Expected to finish
- 2006-12-01
- Last updated by the study team
- 2016-02-03
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
- Siteman Cancer Center at Barnes-Jewish Hospital — St Louis, Missouri, United States
Full record on ClinicalTrials.gov
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