Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
Completed · Phase 2
Conditions studied: Leukemia, Lymphoma
In brief
RATIONALE: Monoclonal antibodies such as rituximab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the numbers of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. Combining chemotherapy with rituximab and filgrastim may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining rituximab with chemotherapy and filgrastim in treating patients who have Burkitt's lymphoma or Burkitt's leukemia.
Key facts
- Study ID
- NCT00039130
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 105
- Starts
- 2002-05-01
- Expected to finish
- 2014-10-01
- Last updated by the study team
- 2023-08-21
Who can join
Age: 16 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Naval Medical Center - San Diego — San Diego, California, United States
- Tunnell Cancer Center at Beebe Medical Center — Lewes, Delaware, United States
- CCOP - Christiana Care Health Services — Newark, Delaware, United States
- Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
- University of Illinois Cancer Center — Chicago, Illinois, United States
- University of Chicago Cancer Research Center — Chicago, Illinois, United States
- Fort Wayne Medical Oncology and Hematology — Fort Wayne, Indiana, United States
- Hematology Oncology Associates of the Quad Cities — Bettendorf, Iowa, United States
- Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
- Greenebaum Cancer Center at University of Maryland Medical Center — Baltimore, Maryland, United States
- Union Hospital Cancer Program at Union Hospital — Elkton, Maryland, United States
- Masonic Cancer Center at University of Minnesota — Minneapolis, Minnesota, United States
- Ellis Fischel Cancer Center at University of Missouri - Columbia — Columbia, Missouri, United States
- Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center — Lebanon, New Hampshire, United States
- Cancer Institute of New Jersey at Cooper - Voorhees — Voorhees Township, New Jersey, United States
- Roswell Park Cancer Institute — Buffalo, New York, United States
- Monter Cancer Center of the North Shore-LIJ Health System — Lake Success, New York, United States
- CCOP - North Shore University Hospital — Manhasset, New York, United States
- Don Monti Comprehensive Cancer Center at North Shore University Hospital — Manhasset, New York, United States
- Long Island Jewish Medical Center — New Hyde Park, New York, United States
- Stony Brook University Cancer Center — Stony Brook, New York, United States
- Presbyterian Cancer Center at Presbyterian Hospital — Charlotte, North Carolina, United States
- Duke Comprehensive Cancer Center — Durham, North Carolina, United States
- Wayne Memorial Hospital, Incorporated — Goldsboro, North Carolina, United States
- Wake Forest University Comprehensive Cancer Center — Winston-Salem, North Carolina, United States
Full record on ClinicalTrials.gov
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