Healthy Aging and Memory Study

Completed

Conditions studied: Alzheimer Disease

In brief

This project will focus on the development and testing of efficient, cost effective measures that are specifically designed for use in Alzheimer's Disease (AD) primary prevention trials.

Key facts

Study ID

NCT00034567

Run by

National Institute on Aging (NIA)

People needed

650

Last updated by the study team

2007-09-18

Who can join

Age: 75 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 75 years or older.
• Fluent in English or Spanish.
• Stable medical condition for four weeks prior to screening visit.
• Stable medications for four weeks prior to screening visit.
• Either cognitively normal, or mild cognitive impairment. If MCI, the subject's CDR at screening have a global score of 0.5.
• mMMSE score greater than 88 for subjects with at least 8 years education, or greater than 80 for subjects with less than 8 years education, and FCSRT total free plus cued recall score greater than 44 with 3 learning trials.
• Willing to participate in four to five year follow-up study.
• Willing to identify person who can serve as informant.
• At least six years education or work history sufficient to exclude mental retardation

You may not qualify if…

• Meets DSM IV criteria for dementia
• History of clinically significant medical illness that would interfere with participation in trial, including active malignancy, myocardial infarction, or cerebrovascular accident within the past year
• Alcohol or substance abuse and/or active major psychiatric disorders
• Concurrent participation in a clinical drug trial
• History of mental retardation

Where it is running

• University of Alabama, Birmingham — Birmingham, Alabama, United States
• Sun Health Research Institute — Sun City, Arizona, United States
• University of California, Irvine — Irvine, California, United States
• University of California, San Diego — La Jolla, California, United States
• University of Southern California — Los Angeles, California, United States
• University of California, Los Angeles — Los Angeles, California, United States
• Stanford/Va Aging Clinical Research Center — Palo Alto, California, United States
• University of California, Davis — Sacramento, California, United States
• Yale University School of Medicine — New Haven, Connecticut, United States
• Georgetown University Medical Center — Washington D.C., District of Columbia, United States
• Baumel-Eisner Neuromedical Institute, Boca Raton — Boca Raton, Florida, United States
• Baumel-Eisner Ft Lauderdale — Fort Lauderdale, Florida, United States
• Mayo Clinic, Jacksonville — Jacksonville, Florida, United States
• Wien Center for Memory Disorders — Miami Beach, Florida, United States
• Baumel-Eisner Neuromedical Institute, Miami Beach — Miami Beach, Florida, United States
• University of South Florida, Tampa — Tampa, Florida, United States
• Emory University — Atlanta, Georgia, United States
• Northwestern University — Chicago, Illinois, United States
• Rush Alzheimer's Disease Center — Chicago, Illinois, United States
• Indiana University Alzheimer's Center — Indianapolis, Indiana, United States
• University of Kentucky, Lexington — Lexington, Kentucky, United States
• Johns Hopkins University — Baltimore, Maryland, United States
• Brigham and Women's Hospital — Boston, Massachusetts, United States
• Boston University School of Medicine — Boston, Massachusetts, United States
• Michigan Alzheimer's Disease Research Center — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

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