A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis
Completed · Phase 1/Phase 2
Conditions studied: Sepsis
In brief
The purpose of this study is to determine whether the administration of the study drug is effective in increasing the chance of survival in patients with severe sepsis. Patients entered into this study will be randomly assigned to one of two treatment groups. Patients in each treatment group will be given either the study drug or placebo as a continuous infusion directly into the bloodstream through a catheter placed in one of the patient's veins. The study drug is an investigational drug that is still in development. It has been studied in approximately 30 healthy subjects, approximately 30 patients with either kidney failure or arthritis, and approximately 600 patients with severe sepsis. Patient participation in this study will last for about one month.
Key facts
- Study ID
- NCT00034476
- Run by
- Eli Lilly and Company
- People needed
- 466
- Starts
- 2001-10-01
- Expected to finish
- 2002-10-01
- Last updated by the study team
- 2006-07-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Study site — Phoenix, Arizona, United States
- Study site — Berkeley, California, United States
- Study site — Los Angeles, California, United States
- Study site — Orange, California, United States
- Study site — San Diego, California, United States
- Study site — Torrance, California, United States
- Study site — Denver, Colorado, United States
- Study site — Washington D.C., District of Columbia, United States
- Study site — Brandon, Florida, United States
- Study site — Clearwater, Florida, United States
- Study site — Lakeland, Florida, United States
- Study site — Miami, Florida, United States
- Study site — Orlando, Florida, United States
- Study site — Tampa, Florida, United States
- Study site — Augusta, Georgia, United States
- Study site — Chicago, Illinois, United States
- Study site — Oak Park, Illinois, United States
- Study site — Springfield, Illinois, United States
- Study site — Indianapolis, Indiana, United States
- Study site — Des Moines, Iowa, United States
- Study site — Iowa City, Iowa, United States
- Study site — Kansas City, Kansas, United States
- Study site — Lexington, Kentucky, United States
- Study site — Lake Charles, Louisiana, United States
- Study site — Birmingham, Alabama, United States
Full record on ClinicalTrials.gov
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