Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

Completed · Phase 3

Conditions studied: Multiple Myeloma and Plasma Cell Neoplasm

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Combining dexamethasone and thalidomide may kill more cancer cells. It is not yet known whether dexamethasone is more effective with or without thalidomide in treating multiple myeloma. PURPOSE: Randomized phase III trial to determine the effectiveness of dexamethasone with or without thalidomide in treating patients who have multiple myeloma.

Key facts

Study ID

NCT00033332

Run by

National Cancer Institute (NCI)

Starts

2002-04-01

Expected to finish

2006-06-01

Last updated by the study team

2014-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Veterans Affairs Medical Center - Palo Alto — Palo Alto, California, United States
• Stanford University Medical Center — Stanford, California, United States
• CCOP - Colorado Cancer Research Program, Inc. — Denver, Colorado, United States
• CCOP - Christiana Care Health Services — Wilmington, Delaware, United States
• MBCCOP - Howard University Cancer Center — Washington D.C., District of Columbia, United States
• Veterans Affairs Medical Center - Gainesville — Gainesville, Florida, United States
• UF Shands Cancer Center — Gainesville, Florida, United States
• Veterans Affairs Medical Center - Miami — Miami, Florida, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Veterans Affairs Medical Center - Tampa (Haley) — Tampa, Florida, United States
• Emory University Hospital - Atlanta — Atlanta, Georgia, United States
• Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
• Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
• Veterans Affairs Medical Center - Lakeside Chicago — Chicago, Illinois, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• CCOP - Evanston — Evanston, Illinois, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• CCOP - Northern Indiana CR Consortium — South Bend, Indiana, United States
• Hematology Oncology Associates of the Quad Cities — Bettendorf, Iowa, United States
• CCOP - Cedar Rapids Oncology Project — Cedar Rapids, Iowa, United States
• CCOP - Scottsdale Oncology Program — Scottsdale, Arizona, United States

Full record on ClinicalTrials.gov

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