Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas
Completed · Phase 2
Conditions studied: Brain and Central Nervous System Tumors
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining temozolomide with radiation therapy in treating patients who have newly diagnosed anaplastic oligodendrogliomas or mixed anaplastic oligoastrocytomas.
Key facts
- Study ID
- NCT00033280
- Run by
- Radiation Therapy Oncology Group
- People needed
- 42
- Starts
- 2002-07-01
- Expected to finish
- 2018-05-14
- Last updated by the study team
- 2020-10-22
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mobile Infirmary Medical Center — Mobile, Alabama, United States
- Foundation for Cancer Research and Education — Phoenix, Arizona, United States
- CCOP - Mayo Clinic Scottsdale Oncology Program — Scottsdale, Arizona, United States
- Shands Cancer Center at the University of Florida Health Science Center — Gainesville, Florida, United States
- Mayo Clinic — Jacksonville, Florida, United States
- University of Miami Sylvester Cancer Center — Miami, Florida, United States
- Baptist Hospital of Miami — Miami, Florida, United States
- Mayo Clinic Cancer Center — Rochester, Minnesota, United States
- CCOP - Kansas City — Kansas City, Missouri, United States
- Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha — Omaha, Nebraska, United States
- Monmouth Medical Center — Long Branch, New Jersey, United States
- Wayne Memorial Hospital, Inc. — Goldsboro, North Carolina, United States
- Rutherford Hospital — Rutherfordton, North Carolina, United States
- CCOP - Southeast Cancer Control Consortium — Winston-Salem, North Carolina, United States
- Akron City Hospital — Akron, Ohio, United States
- Adena Regional Medical Center — Chillicothe, Ohio, United States
- CCOP - Columbus — Columbus, Ohio, United States
- Riverside Methodist Hospital — Columbus, Ohio, United States
- Mount Carmel West Hospital — Columbus, Ohio, United States
- Grady Memorial Hospital — Delaware, Ohio, United States
- Fairfield Medical Center — Lancaster, Ohio, United States
- Strecker Cancer Center at Marietta Memorial Hospital — Marietta, Ohio, United States
- Licking Memorial Hospital — Newark, Ohio, United States
- CCOP - Toledo Community Hospital — Toledo, Ohio, United States
- CCOP - Columbia River Oncology Program — Portland, Oregon, United States
Full record on ClinicalTrials.gov
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