Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)

Completed · Phase 3

Conditions studied: Osteoarthritis

In brief

This study will determine whether glucosamine, chondroitin sulfate and/or the combination of glucosamine and chondroitin sulfate are more effective than placebo and whether the combination is more effective than glucosamine or chondroitin sulfate alone in the treatment of knee pain associated with osteoarthritis (OA) of the knee after six months of follow-up. These substances, marketed in the United States as dietary supplements, have been widely touted by the lay press and by anecdotal personal experience as effective in treating OA. To date, however, only a few small studies have been published in the worldwide literature. The study proposed herein has been carefully constructed to definitively determine the efficacy of these agents.

Key facts

Study ID

NCT00032890

Run by

US Department of Veterans Affairs

People needed

1588

Starts

2000-04-01

Expected to finish

2004-02-01

Last updated by the study team

2009-01-21

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• *University of Arizona Arthritis Center — Tucson, Arizona, United States
• *Cedars-Sinai Medical Center — Los Angeles, California, United States
• *University of California, Los Angeles — Los Angeles, California, United States
• *University of California San Francisco — San Francisco, California, United States
• Northwestern University — Chicago, Illinois, United States
• *Indiana University School of Medicine — Indianapolis, Indiana, United States
• *Arthritis Research and Clinical Centers — Wichita, Kansas, United States
• University of Nebraska Medical Center — Omaha, Nebraska, United States
• Hospital for Joint Diseases — New York, New York, United States
• *Case Western Reserve University — Beachwood, Ohio, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• *University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Arthritis Consultation Center — Dallas, Texas, United States
• *University of Utah — Salt Lake City, Utah, United States
• Virginia Mason Research Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.