Hormone Therapy Plus Chemotherapy in Treating Patients With Prostate Cancer
Completed · Phase 3
Conditions studied: Prostate Cancer
In brief
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as luteinizing hormone-releasing hormone agonist, flutamide, and bicalutamide may stop the adrenal glands from producing androgens. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more tumor cells. It is not yet known whether chemotherapy given at the same time as hormone therapy is more effective than chemotherapy given after hormone therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of chemotherapy given at the same time as hormone therapy with that of chemotherapy given after hormone therapy in treating patients who have prostate cancer.
Key facts
- Study ID
- NCT00030654
- Run by
- Radiation Therapy Oncology Group
- People needed
- 21
- Starts
- 2002-10-01
- Expected to finish
- 2005-02-04
- Last updated by the study team
- 2020-10-22
Who can join
Age: 18 and older, up to 120. Sex: male. Healthy volunteers: not accepted.
Where it is running
- Veterans Affairs Medical Center - Tucson — Tucson, Arizona, United States
- Veterans Affairs Medical Center - Little Rock — Little Rock, Arkansas, United States
- Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
- Medical Center of Aurora - South Campus — Aurora, Colorado, United States
- Boulder Community Hospital — Boulder, Colorado, United States
- Memorial Hospital Cancer Center — Colorado Springs, Colorado, United States
- Penrose Cancer Center at Penrose Hospital — Colorado Springs, Colorado, United States
- Porter Adventist Hospital — Denver, Colorado, United States
- St. Joseph Hospital — Denver, Colorado, United States
- Presbyterian - St. Luke's Medical Center — Denver, Colorado, United States
- Rocky Mountain Cancer Centers - Denver Rose — Denver, Colorado, United States
- CCOP - Colorado Cancer Research Program, Incorporated — Denver, Colorado, United States
- Swedish Medical Center — Englewood, Colorado, United States
- Sky Ridge Medical Center — Lone Tree, Colorado, United States
- Hope Cancer Care Center at Longmont United Hospital — Longmont, Colorado, United States
- St. Mary-Corwin Regional Medical Center — Pueblo, Colorado, United States
- Rocky Mountain Cancer Centers - Thornton — Thornton, Colorado, United States
- Shands Cancer Center at the University of Florida Health Science Center — Gainesville, Florida, United States
- University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
- Gulf Coast Cancer Treatment Center — Panama City, Florida, United States
- Tallahassee Memorial Hospital — Tallahassee, Florida, United States
- Veterans Affairs Medical Center - Tampa (Haley) — Tampa, Florida, United States
- Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center — Boise, Idaho, United States
- Veterans Affairs Medical Center - Hines — Hines, Illinois, United States
- Foundation for Cancer Research and Education — Phoenix, Arizona, United States
Full record on ClinicalTrials.gov
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