Docetaxel With or Without Oblimersen in Treating Patients With Non-Small Cell Lung Cancer

Status unconfirmed · Phase 2/Phase 3

Conditions studied: Lung Cancer

In brief

RATIONALE: Drugs used in chemotherapy such as docetaxel use different ways to stop tumor cells from dividing so they stop growing or die. Oblimersen may increase the effectiveness of docetaxel by making the tumor cells more sensitive to the drug. It is not yet known if docetaxel is more effective with or without oblimersen in treating non-small cell lung cancer. PURPOSE: Randomized phase II/III trial to compare the effectiveness of docetaxel with or without oblimersen in treating patients who have relapsed or refractory non-small cell lung cancer that has been previously treated.

Key facts

Study ID

NCT00030641

Run by

Genta Incorporated

Starts

2001-10-01

Last updated by the study team

2014-01-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
• Montgomery Cancer Center — Montgomery, Alabama, United States
• Little Rock Hematology-Oncology Associates — Little Rock, Arkansas, United States
• East Bay Medical Oncology — Concord, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Medical Oncology Care Associates — Orange, California, United States
• Pacific Hematology/Oncology — San Francisco, California, United States
• John Wayne Cancer Institute at Saint John's Health Center — Santa Monica, California, United States
• University of Colorado Cancer Center at University of Colorado Health Sciences Center — Aurora, Colorado, United States
• Whittingham Cancer Center — Norwalk, Connecticut, United States
• Lakeland Regional Cancer Center — Lakeland, Florida, United States
• Georgia Cancer Specialists - Northside Office — Atlanta, Georgia, United States
• Augusta Oncology Associates — Augusta, Georgia, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• CCOP - Northern Indiana CR Consortium — South Bend, Indiana, United States
• Central Baptist Hospital — Lexington, Kentucky, United States
• Hematology Oncology Services — New Orleans, Louisiana, United States
• Louisiana State University Health Sciences Center - Shreveport — Shreveport, Louisiana, United States
• Josephine Ford Cancer Center at Henry Ford Hospital — Detroit, Michigan, United States
• Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha — Omaha, Nebraska, United States
• Summit Medical Group, P.A. — Summit, New Jersey, United States
• Winthrop University Hospital — Mineola, New York, United States
• North General Hospital — New York, New York, United States
• Veterans Affairs Medical Center - Oklahoma City — Oklahoma City, Oklahoma, United States
• Charleston Cancer Center — Charleston, South Carolina, United States

Full record on ClinicalTrials.gov

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