Chemotherapy and Photodynamic Therapy in Treating Patients With Cutaneous T-Cell Lymphoma

Status unconfirmed · Phase 2

Conditions studied: Lymphoma

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill cancer cells. Photosensitizing drugs, such as methoxsalen, are absorbed by cancer cells and, when exposed to light, become active and kill the cancer cells. Combining chemotherapy with photodynamic therapy may be an effective treatment for cutaneous T-cell lymphoma. PURPOSE: Randomized phase II trial to study the effectiveness of combining different doses of bexarotene with photodynamic therapy in treating patients who have stage IB or stage IIA cutaneous T-cell lymphoma.

Key facts

Study ID

NCT00030589

Run by

Millennix

Starts

2001-02-01

Last updated by the study team

2013-12-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Stanford University Medical Center — Stanford, California, United States
• University of Colorado Health Science Center — Aurora, Colorado, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Northwestern University Medical Center — Chicago, Illinois, United States
• Rush-Presbyterian-St. Luke's Medical Center — Chicago, Illinois, United States
• Tulane University School of Medicine — New Orleans, Louisiana, United States
• Study site — Slidell, Louisiana, United States
• Boston Medical Center — Boston, Massachusetts, United States
• Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
• Henry Ford Hospital — Detroit, Michigan, United States
• StonyBrook Dermatology Associates, P.C. — East Setauket, New York, United States
• St. Luke's-Roosevelt Hospital Center - Roosevelt Division — New York, New York, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• Knoxville Dermatology Group, P.C. — Knoxville, Tennessee, United States
• Simmons Cancer Center - Dallas — Dallas, Texas, United States
• University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
• Study site — Tyler, Texas, United States

Full record on ClinicalTrials.gov

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