Garlic in Hyperlipidemia Caused by HAART

Withdrawn before enrolling · Phase 2

Conditions studied: HIV Infections, Hypercholesterolemia, Hypertriglyceridemia, Hyperglycemia

In brief

The purpose of this study is to test the effectiveness and tolerability of garlic pills in lowering cholesterol and triglycerides in hyperlipidemic HIV-infected individuals who are being treated with highly active antiretroviral therapy (HAART).

Key facts

Study ID

NCT00029250

Run by

National Center for Complementary and Integrative Health (NCCIH)

People needed

0

Starts

2001-11-01

Expected to finish

2003-05-01

Last updated by the study team

2013-03-22

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• HIV-1 seropositive confirmed by medical history
• On stable HAART for at least 6 months before study entry without the likelihood of HAART therapy changes in the following 6 months due to viral rebound or adverse events
• CD4+ lymphocyte number > 100 cells/mm3 measured within 60 days before study entry
• HIV-1 viral load < 2000 RNA copies/ml
• Cholesterol > 200 mg/dL
• Triglycerides > 250 mg/dL < 1000 mg/dL
• Willing and able to avoid raw or dry garlic, onion, leeks and shallots as well as supplements containing garlic during the 16 weeks of the trial
• Willing and able to provide inform consent
• Willing and able to understand and follow protocol for the duration of the study
• Willing and able to maintain a consistent lifestyle routine, eg. diet, exercise, medications, dietary supplements and sleep schedule for the duration of the study
• Willing and able to understand and follow the Step 1 guidelines from the National Cholesterol Education Program (NCEP) for the duration of the study
• Willing to remain adherent to the current HAART regimen

Where it is running

• Bastyr University Center for Natural Health — Seattle, Washington, United States
• University of Washington Harborview Medical Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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