Study of Dehydrex in Patients With Corneal Erosion
Completed · Not applicable
Conditions studied: Corneal Diseases, Recurrence
In brief
This is a compassionate-use treatment study to provide Dehydrex to patients with corneal erosion syndrome who have previously used Dehydrex.
Key facts
- Study ID
- NCT00029185
- Run by
- Holles Laboratories, Inc.
- People needed
- 300
- Starts
- 2001-09-01
- Expected to finish
- 2007-09-01
- Last updated by the study team
- 2015-03-25
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Clinical diagnosis of symptomatic recurrent corneal syndrome due to anterior membrane dystrophy or posttraumatic abrasion
- Not responsive to standard medical therapy with artificial tears, hypertonic saline, or bandage soft contact lenses
- At least 3 episodes of erosion within the past 4 months documented by slit lamp examination
You may not qualify if…
- Allergy to any component of the medications to be used
- Active ocular surface infection due to bacteria, virus, or fungus
- Chronic atopic disease affecting the ocular surface or adnexa
- Dry eye, exposure, trichiasis, entropion, ectropion, or neurotrophic keratopathy
- Concurrent use of contact lenses
- Diagnosis of persistent epithelial defect in eye to be treated
- Concurrent use of topical medication to eye to be treated
- Any ocular eyelid surgery within the past 6 months
- Pre-existing corneal stromal edema
- Diabetes mellitus
- Postsurgical infection
- Dry eye condition of 16 or greater on Patient's Dry Eye Questionnaire
- Other investigational medications within the past 6 months
- Other corneal dystrophy
Where it is running
- Holles Laboratories, Inc. — Cohasset, Massachusetts, United States
Full record on ClinicalTrials.gov
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