Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission

Completed

Conditions studied: HIV Infections, Pregnancy Complications, Infectious

In brief

The purpose of this study is to collect and study clinical and laboratory information about a pregnant or new mother and her medical care that will increase our knowledge of the best care for HIV-infected pregnant women and their children. The rate of transmission of HIV from mothers to their infants has gone down. Specific U.S. Public Health Service guidelines recommend that HIV-infected pregnant women be treated with anti-HIV therapies; but the effectiveness of treatment and safety for the mother and her infant have not been fully examined. This study will monitor the health of women and their infants while they receive anti-HIV therapy. Also, this study will provide information that may be used for future studies.

Key facts

Study ID

NCT00028145

Run by

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

People needed

3090

Starts

2002-10-01

Expected to finish

2013-06-01

Last updated by the study team

2014-10-10

Who can join

Age: 14 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• HIV infected
• At least 14 weeks pregnant OR have delivered a liveborn or stillborn infant and are within 14 days of the delivery
• Currently receiving care at an IMPAACT or other participating site
• Have a parent or guardian willing to provide signed informed consent, if applicable
• Mentally capable of giving informed consent to have the infant and self followed at an IMPAACT site

You may not qualify if…

• Intend to end the pregnancy
• Unable to come for a study visit within 14 days after delivery (if known to be HIV infected prior to delivery) OR within 28 days after delivery (if found to be HIV infected at the time of labor and delivery or within 14 days after delivery)

Where it is running

• University of South Alabama — Mobile, Alabama, United States
• Phoenix Childrens Hospital — Phoenix, Arizona, United States
• Long Beach Memorial (Pediatric) — Long Beach, California, United States
• Miller Children's Hospital Long Beach (5093) — Long Beach, California, United States
• Los Angeles County Medical Center/USC — Los Angeles, California, United States
• Usc La Nichd Crs (5048) — Los Angeles, California, United States
• UCLA Med Ctr / Pediatric — Los Angeles, California, United States
• UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CR (3601) — Los Angeles, California, United States
• Univ of California, San Diego (4601) — San Diego, California, United States
• Univ. of California San Francisco NICHD CRS (5091) — San Francisco, California, United States
• Harbor-UCLA Med Ctr (5045) — Torrance, California, United States
• University of Colorado Denver NICHD CRS (5052) — Denver, Colorado, United States
• Connecticut Childrens Medical Center (Pediatric) — Farmington, Connecticut, United States
• University of Connecticut, Farmington — Farmington, Connecticut, United States
• Yale Univ School of Med — New Haven, Connecticut, United States
• Children's National Medical Center Washington DC NICHD CRS (5015) — Washington D.C., District of Columbia, United States
• Washington Hospital Center NICHD CRS (5023) — Washington D.C., District of Columbia, United States
• Howard Univ Hosp (5044) — Washington D.C., District of Columbia, United States
• North Broward Hosp District — Fort Lauderdale, Florida, United States
• South Florida CDC Ft Lauderdale NICHD CRS (5055) — Fort Lauderdal, Florida, United States
• University of Florida Jacksonville (5051) — Jacksonville, Florida, United States
• Jackson Memorial Hosp — Miami, Florida, United States
• University of Miami Pediatric/Perinatal HIV/AIDS (4201) — Miami, Florida, United States
• University of South Florida at Tampa (5018) — St. Petersburg, Florida, United States
• Univ. of Alabama Birmingham NICHD CRS (5096) — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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