Use of a Test That Evaluates How the Body Handles Insulin and Glucose

Completed

Conditions studied: HIV Infections

In brief

The purpose of this study is to find out if testosterone gel affects how the body handles insulin and glucose. Specific anti-HIV treatments may increase a patient's risk of certain diseases by causing metabolic problems such as reduced sensitivity to insulin. This substudy will examine how testosterone affects insulin sensitivity. If testosterone increases insulin sensitivity in the patients, then giving testosterone to HIV-infected patients may allow the continuation of anti-HIV treatments without increasing the patients' risk of disease. The test used to determine insulin sensitivity will be a modified frequently sampled intravenous glucose tolerance test (FSIVGTT), which can accurately measure insulin sensitivity.

Key facts

Study ID

NCT00027092

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

50

Last updated by the study team

2008-08-07

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Patients may be eligible for this study if they:
• Are enrolled in A5079.

Where it is running

• Univ of Southern California / LA County USC Med Ctr — Los Angeles, California, United States
• Univ of California San Francisco — San Francisco, California, United States
• Univ of Hawaii — Honolulu, Hawaii, United States
• Rush Presbyterian - Saint Luke's Med Ctr — Chicago, Illinois, United States
• Indiana Univ Hosp — Indianapolis, Indiana, United States
• Methodist Hosp of Indiana / Life Care Clinic — Indianapolis, Indiana, United States
• Wishard Hosp — Indianapolis, Indiana, United States
• Bellevue Hosp / New York Univ Med Ctr — New York, New York, United States

Full record on ClinicalTrials.gov

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