A Study of Decreased Mental Function Associated With HIV
Completed · Not applicable
Conditions studied: Cognitive Disorders, HIV Infections
In brief
The purpose of this study is to compare pictures of the brain of HIV-infected people with memory problems before and after treatment with selegiline. Selegiline is the study drug received through A5090. HIV patients generally develop memory problems late in the disease. This will be examined using noninvasive proton magnetic resonance spectroscopy (1H-MRS). The effect of the drug selegiline on memory problems also will be examined.
Key facts
- Study ID
- NCT00027040
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 90
- Expected to finish
- 2005-06-01
- Last updated by the study team
- 2015-01-16
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients may be eligible for this study if they:
- Are enrolled in ACTG protocol A5090.
- Meet the inclusion/exclusion criteria set forth for the Step 1 phase of AACTG protocol A5090.
You may not qualify if…
- Patients will not be eligible for this study if they have:
- Claustrophobia (unless sedation with lorazepam or zolpidem allows for safe performance of the MRS).
- Metallic implants/medical devices (e.g., skull implants or cardiac devices).
Where it is running
- UCLA CARE Ctr — Los Angeles, California, United States
- Univ of California, San Diego — San Diego, California, United States
- Stanford University — Stanford, California, United States
- Johns Hopkins Hosp — Baltimore, Maryland, United States
- Mount Sinai Med Ctr — New York, New York, United States
- Columbia Presbyterian Med Ctr — New York, New York, United States
- Univ of Rochester Medical Center — Rochester, New York, United States
- Univ of Pennsylvania — Philadelphia, Pennsylvania, United States
- Rhode Island Hosp — Providence, Rhode Island, United States
- Stanley Street Treatment and Resource — Providence, Rhode Island, United States
- The Miriam Hosp — Providence, Rhode Island, United States
- Univ of Washington — Seattle, Washington, United States
Full record on ClinicalTrials.gov
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