Biological Specimen Collection for Laboratory Methods Development and Training Purposes
Completed
Conditions studied: Healthy
In brief
This study will collect biological samples-buccal cells, blood sample, skin sample-to be used in developing and testing laboratory methods for measuring and analyzing genes. Such methods can be used for research on identifying genetic factors that may affect a person's cancer risk. All individuals age 21 and older may participate in this study. Participants will provide one or more of the following samples: * Buccal (mouth) cells - obtained by swishing a small amount of mouthwash in the mouth or by swabbing or bushing the inside of the cheek with a swab or brush. * Blood - obtained by pricking the finger and collecting the drops or by blood drawing through a needle placed in an arm vein. * Skin - obtained by a punch biopsy on the inner upper arm. For this procedure, the skin is anesthetized and a small piece of skin is removed with a sharp instrument similar to a cookie cutter. The wound is then covered and held together with a sterile bandage. A small scar, approximately 1/8-inch long, will be left. Most participants will be asked to provide only a buccal sample; blood and/or skin samples will be requested from a few participants. The blood and skin samples may be used to grow cell lines; that is, to make them grow indefinitely for research uses.
Key facts
- Study ID
- NCT00025831
- Run by
- National Cancer Institute (NCI)
- People needed
- 200
- Starts
- 2001-10-01
- Expected to finish
- 2005-09-01
- Last updated by the study team
- 2008-03-04
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Participants who have volunteered for previous DCEG studies within the past three years in which buccal or blood samples were collected will be excluded because the samples collected in the current study may be combined with some previously collected samples and duplication of subjects is to be avoided.
- Individuals with known active oral disease will be excluded from the buccal cell collection component, and those known to form keloids will be excluded from the skin biopsy component.
Where it is running
- National Cancer Institute (NCI) — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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