Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Brain Cancer

Completed · Phase 1

Conditions studied: Brain and Central Nervous System Tumors

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation or bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining temozolomide, thiotepa, and carboplatin followed by peripheral stem cell transplantation or bone marrow transplantation in treating patients who have brain cancer.

Key facts

Study ID

NCT00025558

Run by

NYU Langone Health

Starts

2000-10-01

Last updated by the study team

2011-03-28

Who can join

Age: 1 and older, up to 49. Sex: any. Healthy volunteers: not accepted.

Where it is running

• NYU Cancer Institute at New York University Medical Center — New York, New York, United States
• Columbus Children's Hospital — Columbus, Ohio, United States
• Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
• Princess Margaret Hospital for Children — Perth, Western Australia, Australia

Full record on ClinicalTrials.gov

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