Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)
Stopped early · Phase 3
Conditions studied: Colorectal Cancer, Metastatic Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping the cells from dividing. Chemoembolization kills tumor cells by blocking the blood flow to the tumor and keeping chemotherapy drugs near the tumor. It is not yet known if chemoembolization is more effective than standard chemotherapy in treating metastatic cancer. PURPOSE: This phase I trial and randomized phase III trial is studying the effectiveness of chemoembolization in treating patients who have colorectal cancer metastatic to the liver.
Key facts
- Study ID
- NCT00023868
- Run by
- American College of Radiology Imaging Network
- Starts
- 2001-11-01
- Expected to finish
- 2002-09-25
- Last updated by the study team
- 2020-12-02
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Arizona Cancer Center — Tucson, Arizona, United States
- H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
- Robert H. Lurie Comprehensive Cancer Center, Northwestern University — Chicago, Illinois, United States
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
- NYU School of Medicine's Kaplan Comprehensive Cancer Center — New York, New York, United States
- State University of New York - Upstate Medical University — Syracuse, New York, United States
- University of Pennsylvania Cancer Center — Philadelphia, Pennsylvania, United States
- University of Texas - MD Anderson Cancer Center — Houston, Texas, United States
Full record on ClinicalTrials.gov
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