Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma

Completed · Phase 1/Phase 2

Conditions studied: Sarcoma

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving chemotherapy, SU5416, and radiation therapy before and after surgery may kill more tumor cells. PURPOSE: Phase I/II trial to study the effectiveness of chemotherapy, SU5416, radiation therapy, and surgery in treating patients who have soft tissue sarcoma.

Key facts

Study ID

NCT00023738

Run by

Radiation Therapy Oncology Group

Starts

2001-08-01

Expected to finish

2003-10-01

Last updated by the study team

2013-06-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Huntsville Hospital System — Huntsville, Alabama, United States
• Comprehensive Cancer Institute of Huntsville — Huntsville, Alabama, United States
• MBCCOP - Gulf Coast — Mobile, Alabama, United States
• Alabama Oncology, LLC — Montgomery, Alabama, United States
• Radiation Oncology Associates of West Alabama — Tuscallosa, Alabama, United States
• Foundation for Cancer Research and Education — Phoenix, Arizona, United States
• Mount Diablo Medical Center — Concord, California, United States
• Cancer Center and Beckman Research Institute, City of Hope — Duarte, California, United States
• California Cancer Center — Fresno, California, United States
• Saint Agnes Cancer Center — Fresno, California, United States
• Sutter Health West Cancer Research Group — Greenbrae, California, United States
• Loma Linda University Medical Center — Loma Linda, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Huntington Cancer Center — Pasadena, California, United States
• Cancer Care Center — Pomona, California, United States
• Radiation Oncology Center - Sacramento — Sacramento, California, United States
• Radiation Medical Group, Inc. — San Diego, California, United States
• UCSF Cancer Center and Cancer Research Institute — San Francisco, California, United States
• O'Connor Hospital — San Jose, California, United States
• CCOP - Santa Rosa Memorial Hospital — Santa Rosa, California, United States
• David Grant Medical Center — Travis Air Force Base, California, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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