Tipifarnib in Treating Young Patients With Refractory Leukemia

Completed · Phase 1

Conditions studied: Leukemia

In brief

RATIONALE: Tipifarnib may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. PURPOSE: Phase I trial to study the effectiveness of tipifarnib in treating young patients who have refractory leukemia.

Key facts

Study ID

NCT00022451

Run by

National Institutes of Health Clinical Center (CC)

Starts

2001-06-01

Expected to finish

2005-03-01

Last updated by the study team

2012-03-15

Who can join

Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• UCSF Comprehensive Cancer Center — San Francisco, California, United States
• Stanford Cancer Center at Stanford University Medical Center — Stanford, California, United States
• Children's National Medical Center — Washington D.C., District of Columbia, United States
• Shands Cancer Center at the University of Florida Health Science Center — Gainesville, Florida, United States
• AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus — Atlanta, Georgia, United States
• MBCCOP-Medical College of Georgia Cancer Center — Augusta, Georgia, United States
• Children's Memorial Hospital - Chicago — Chicago, Illinois, United States
• Riley Children Cancer Center at Riley Hospital for Children — Indianapolis, Indiana, United States
• Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center — Kansas City, Kansas, United States
• MBCCOP - LSU Health Sciences Center — New Orleans, Louisiana, United States
• Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins — Baltimore, Maryland, United States
• Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support — Bethesda, Maryland, United States
• Floating Hospital for Children — Boston, Massachusetts, United States
• Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute — Boston, Massachusetts, United States
• University of Michigan Comprehensive Cancer Center — Ann Arbor, Michigan, United States
• Children's Hospital of Michigan — Detroit, Michigan, United States
• University of Minnesota Cancer Center — Minneapolis, Minnesota, United States
• Mayo Clinic Cancer Center — Rochester, Minnesota, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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