Radiation Therapy and Paclitaxel, Carboplatin, and Fluorouracil Followed by Esophagectomy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction
Completed · Phase 2
Conditions studied: Esophageal Cancer, Gastric Cancer
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy, such as paclitaxel, carboplatin, and fluorouracil, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving radiation therapy with chemotherapy and giving them before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: This phase II trial is studying how well giving radiation therapy together with combination chemotherapy followed by esophagectomy works in treating patients with locally advanced cancer of the esophagus or gastroesophageal junction.
Key facts
- Study ID
- NCT00022139
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 56
- Starts
- 2002-01-01
- Expected to finish
- 2009-01-01
- Last updated by the study team
- 2016-12-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Cancer Center of Kansas, PA - Chanute — Chanute, Kansas, United States
- Cancer Center of Kansas, PA - Dodge City — Dodge City, Kansas, United States
- Cancer Center of Kansas, PA - El Dorado — El Dorado, Kansas, United States
- Cancer Center of Kansas, PA - Kingman — Kingman, Kansas, United States
- Southwest Medical Center — Liberal, Kansas, United States
- Cancer Center of Kansas, PA - Newton — Newton, Kansas, United States
- Cancer Center of Kansas, PA - Parsons — Parsons, Kansas, United States
- Cancer Center of Kansas, PA - Pratt — Pratt, Kansas, United States
- Cancer Center of Kansas, PA - Salina — Salina, Kansas, United States
- Cancer Center of Kansas, PA - Wellington — Wellington, Kansas, United States
- Associates in Womens Health, PA - North Review — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Medical Arts Tower — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Wichita — Wichita, Kansas, United States
- CCOP - Wichita — Wichita, Kansas, United States
- Via Christi Cancer Center at Via Christi Regional Medical Center — Wichita, Kansas, United States
- Wesley Medical Center — Wichita, Kansas, United States
- Cancer Center of Kansas, PA - Winfield — Winfield, Kansas, United States
- Fairview Ridges Hospital — Burnsville, Minnesota, United States
- Mercy and Unity Cancer Center at Mercy Hospital — Coon Rapids, Minnesota, United States
- Duluth Clinic Cancer Center - Duluth — Duluth, Minnesota, United States
- CCOP - Duluth — Duluth, Minnesota, United States
- Miller - Dwan Medical Center — Duluth, Minnesota, United States
- Fairview Southdale Hospital — Edina, Minnesota, United States
- Mercy and Unity Cancer Center at Unity Hospital — Fridley, Minnesota, United States
- Minnesota Oncology Hematology, PA - Maplewood — Maplewood, Minnesota, United States
Full record on ClinicalTrials.gov
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