Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer
Completed · Phase 2
Conditions studied: Colorectal Cancer
In brief
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy and chemotherapy may shrink the tumor so that it can be removed during surgery. PURPOSE: Phase II trial to study the effectiveness of radiation therapy and chemotherapy followed by surgery and combination chemotherapy in treating patients who have stage II or stage III rectal cancer.
Key facts
- Study ID
- NCT00021398
- Run by
- Fox Chase Cancer Center
- People needed
- 23
- Starts
- 1996-07-01
- Expected to finish
- 2018-09-01
- Last updated by the study team
- 2020-06-05
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Hunterdon Regional Cancer Center — Flemington, New Jersey, United States
- Kimball Medical Center — Lakewood, New Jersey, United States
- Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County — Mount Holly, New Jersey, United States
- Riverview Medical Center — Red Bank, New Jersey, United States
- Community Medical Center — Toms River, New Jersey, United States
- St. Francis Medical Center — Trenton, New Jersey, United States
- Bon Secours-Holy Family Health System — Altoona, Pennsylvania, United States
- Delaware County Memorial Hospital — Drexel Hill, Pennsylvania, United States
- Pinnacle Health Hospitals — Harrisburg, Pennsylvania, United States
- Conemaugh Memorial Hospital — Johnstown, Pennsylvania, United States
- Saint Mary Regional Center — Langhorne, Pennsylvania, United States
- North Penn Hospital — Lansdale, Pennsylvania, United States
- Paoli Memorial Hospital — Paoli, Pennsylvania, United States
- Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States
- Pottstown Memorial Regional Cancer Center — Pottstown, Pennsylvania, United States
- Reading Hospital and Medical Center — Reading, Pennsylvania, United States
- Southern Chester County Medical Center — West Grove, Pennsylvania, United States
Full record on ClinicalTrials.gov
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