Rituximab Plus Fludarabine in Treating Patients With Waldenstrom's Macroglobulinemia

Completed · Phase 2

Conditions studied: Lymphoma

In brief

RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different way to stop cancer cells from dividing so they stop growing or die. Combining monoclonal antibody therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of rituximab plus fludarabine in treating patients who have Waldenstrom's macroglobulinemia.

Key facts

Study ID

NCT00020800

Run by

Jonsson Comprehensive Cancer Center

People needed

7

Starts

2001-09-01

Last updated by the study team

2013-01-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Arizona Cancer Center — Tucson, Arizona, United States
• Cedars-Sinai Medical Center — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• Rush-Presbyterian-St. Luke's Medical Center — Chicago, Illinois, United States
• Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
• Marlene and Stewart Greenebaum Cancer Center, University of Maryland — Baltimore, Maryland, United States
• Tuft-New England Medical Center — Boston, Massachusetts, United States
• Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Long Island Jewish Medical Center — New Hyde Park, New York, United States
• Memorial Sloan-Kettering Cancer Center — New York, New York, United States
• Barrett Cancer Center — Cincinnati, Ohio, United States
• Cleveland Clinic Taussig Cancer Center — Cleveland, Ohio, United States
• Cross Cancer Institute — Edmonton, Alberta, Canada
• Chedoke-McMaster Hospitals — Hamilton, Ontario, Canada
• Huddinge University Hospital — Stockholm, Sweden
• Saint Bartholomew's Hospital — London, England, United Kingdom

Full record on ClinicalTrials.gov

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