Lobradimil and Carboplatin in Treating Children With Brain Tumors

Completed · Phase 2

Conditions studied: Brain and Central Nervous System Tumors

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Lobradimil may increase the effectiveness of a chemotherapy drug by making tumor cells more sensitive to the drug. PURPOSE: Phase II trial to study the effectiveness of carboplatin and lobradimil in treating children with brain tumors that have not responded to previous treatment.

Key facts

Study ID

NCT00019422

Run by

National Cancer Institute (NCI)

Starts

1998-03-01

Expected to finish

2003-04-01

Last updated by the study team

2013-08-16

Who can join

Age: any, up to 21. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of South Alabama Medical Center — Mobile, Alabama, United States
• Phoenix Children's Hospital — Phoenix, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
• Southern California Permanente Medical Group — Downey, California, United States
• City of Hope Comprehensive Cancer Center — Duarte, California, United States
• Rebecca and John Moores UCSD Cancer Center — La Jolla, California, United States
• Loma Linda University Medical Center — Loma Linda, California, United States
• Jonathan Jaques Children's Cancer Center — Long Beach, California, United States
• Children's Hospital Los Angeles — Los Angeles, California, United States
• Cedars-Sinai Medical Center — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Children's Hospital Central California — Madera, California, United States
• Children's Hospital of Oakland — Oakland, California, United States
• Chao Family Comprehensive Cancer Center — Orange, California, United States
• Children's Hospital of Orange County — Orange, California, United States
• Lucile Packard Children's Hospital at Stanford — Palo Alto, California, United States
• Sutter Cancer Center — Sacramento, California, United States
• University of California Davis Medical Center — Sacramento, California, United States
• Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego — San Diego, California, United States
• Children's Hospital San Diego — San Diego, California, United States
• Kaiser Permanente Medical Center - San Francisco Geary Campus — San Francisco, California, United States
• UCSF Comprehensive Cancer Center — San Francisco, California, United States
• Santa Barbara Cottage Hospital — Santa Barbara, California, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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