Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia
Withdrawn before enrolling · Phase 3
Conditions studied: Leukemia
In brief
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Giving radiation therapy to the head or intrathecal chemotherapy may prevent cancer cells from spreading to the brain. It is not yet known which treatment regimen is more effective for acute lymphoblastic leukemia. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy to the head or intrathecal chemotherapy plus high dose cytarabine in preventing CNS disease in children who have acute lymphoblastic leukemia.
Key facts
- Study ID
- NCT00019409
- Run by
- National Institutes of Health Clinical Center (CC)
- People needed
- 0
- Starts
- 1999-10-01
- Expected to finish
- 2001-07-01
- Last updated by the study team
- 2012-03-23
Who can join
Age: 1 and older, up to 20. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Pediatric Oncology Branch — Bethesda, Maryland, United States
- Texas Tech University Health Sciences Center School of Medicine — Amarillo, Texas, United States
- Kidwai Memorial Institute of Oncology — Bangalore, India
- Cancer Institute (W.I.A.) — Madras, India
- Tata Memorial Centre — Mumbai, India
- All-India Institute of Medical Sciences — New Delhi, India
Full record on ClinicalTrials.gov
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