Radiation Therapy in Treating Patients With Glioblastoma

Completed · Phase 1

Conditions studied: Brain and Central Nervous System Tumors

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as pentoxifylline and hydroxyurea may make tumor cells more sensitive to radiation therapy. PURPOSE: Phase I trial to study the effectiveness of radiation therapy plus pentoxifylline and hydroxyurea in treating patients who have high-grade astrocytoma or glioblastoma.

Key facts

Study ID

NCT00019058

Run by

National Cancer Institute (NCI)

People needed

34

Starts

1995-04-01

Last updated by the study team

2015-04-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Radiation Oncology Branch — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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